Abstract
Time
dependent (TD) Monte Carlo (TDMC) photon-tissue interactions simulation program
code generated photon fluencies (Joule/cm²) for ten picosecond (ps) time series
[100 , 200, … 1000] for Continuous Wave
(CW) laser source. TD MC ANSI Standard C program code “trmc.c” was modified and
compiled to generate photon fluence distributions inside the imaging tissue
model. Cylindrical coordinate system was chosen to compile the ANSI standard C
based photon walk program code. Radial r, and depth z axis created cylindrical
mesh grid (r, z) array. Collimated isotropic point laser source within a
semi-infinite homogeneous medium was used. Radial diameter of cylindrical
coordinate system 2r = 6.0 cm, depth z = 3.0 cm. In this study, TD analysis of
CW MC photon fluencies for the photon-tissue interactions simulation mesh grid
geometry for Nz = 30, and Nr = 30 dimensions within 3 cm x 6 cm was performed.
In the MC simulation program code, the tissue absorption and scattering
coefficients were chosen as a = 0, and s = 100 cm-1.
60.000 photons were sent into the tissue from (x, y, z) = (3.0, 3.0, 3.0) cm
isotropic laser source position. The values of photon fluencies are varying
depend on the time in tissue environment were recorded in the ANSI standard C
program data output file. The time intervals were chosen by 100 picosecond (ps)
steps, from 100 ps to 1000 ps sequentially. Depend on the increasing time
steps, CW photon migration was observed inside the tissue, successfully. TD
analysis of CW photon fluencies will be used when making the time resolved
diffuse optic tomography (TRDOT) device. Forward model problem weight matrix
will be built based on the TD distributions of MC photon fluencies, then photon
fluencies will be used in the inverse problem solution image reconstruction
algorithm. The location of buried inclusions will be determined.
References
- S.L. Jacques, https://omlc.org/classroom/ece532/class4/trmc/trmc.c Patterson, M.S., Chance, B., & Wilson, B.C. (1989). Time resolved reflectance and transmittance for the non-invasive measurement of tissue optical properties. Applied Optics, 28(12), 2331-2336. Ueda, Y., Ohta, K., & Yamashita, Y., (2005). Diffuse Optical Tomography using Time-resolved Photon Path Distribution, Optical Review, 12(4), 334–337. Sakami, M., & Mitra, K. (2002). Analysis of short-pulse laser photon transport through tissues for optical tomography, Optics Letters, 27(5), 336-338. Delpy, D.T., Cope, M., Zee, P., Arridge, S., Wray, S., & Wyatt, J. (1988). Estimation of optical pathlength through tissue from direct time of flight measurement. Phys. Med. Biol., 33(12), 1433-1442. S. Landgraf. (2003). Application of laser diodes and ultrabright light emitting diodes for static and time-resolved optical methods in physical chemistry. Handbook of Luminescence, Display Materials and Devices, 3, 372-394.
Abstract
References
- S.L. Jacques, https://omlc.org/classroom/ece532/class4/trmc/trmc.c Patterson, M.S., Chance, B., & Wilson, B.C. (1989). Time resolved reflectance and transmittance for the non-invasive measurement of tissue optical properties. Applied Optics, 28(12), 2331-2336. Ueda, Y., Ohta, K., & Yamashita, Y., (2005). Diffuse Optical Tomography using Time-resolved Photon Path Distribution, Optical Review, 12(4), 334–337. Sakami, M., & Mitra, K. (2002). Analysis of short-pulse laser photon transport through tissues for optical tomography, Optics Letters, 27(5), 336-338. Delpy, D.T., Cope, M., Zee, P., Arridge, S., Wray, S., & Wyatt, J. (1988). Estimation of optical pathlength through tissue from direct time of flight measurement. Phys. Med. Biol., 33(12), 1433-1442. S. Landgraf. (2003). Application of laser diodes and ultrabright light emitting diodes for static and time-resolved optical methods in physical chemistry. Handbook of Luminescence, Display Materials and Devices, 3, 372-394.
Details
| Primary Language | English |
|---|---|
| Subjects | Engineering |
| Journal Section | Articles |
| Authors | |
| Publication Date | December 4, 2018 |
| Published in Issue | Year 2018Issue: 4 |
