Research Article
Year 2019,
Volume: 6 , 106 - 110, 25.07.2019
Abstract
References
- Arnold J. Felsenfeld, Mariano Rodriguez, Escolastico Aguilera-Tejero. “Dynamics of Parathyroid Hormone Secretion in Healthand Secondary Hyperparathyroidism” In –Depth Review; Clin J Am Soc Nephrol 2: 1283-1305, 2007. Bellavia D., Costa V., De Luca A., et al. Vitamin D level between calcium-phosphorus homeostasis and immune system: new perspective in osteoporosis. Current Osteoporosis Reports. 2016:1–12. doi: 10.1007/s11914-016-0331-2. [PubMed] [CrossRef] [Google Scholar] Brown EM: The calcium-sensing receptor: physiology, pathophysiology and CaR-based therapeutics. Subcell Biochem 45: 139–167, 2007 CrossRefPubMedGoogle Scholar Cashman K. D., Dowling K. G., Škrabáková Z. et al., “Vitamin D deficiency in Europe: pandemic?” American Journal of Clinical Nutrition, vol. 103, no. 4, pp. 1033–1044, 2016. View at Publisher • View at Google Scholar • View at Scopus Dawson-Huges B, Haeney RP, Holick MF, Lips P, Meunier PJ, Vieth R: Estimates of optional vitamin D status. Osteoporosis Int 16: 713-716, 2005. Guilsun Kim1*, Ki Won Oh2*, Eun-Hee Jang3, Mee-Kyoung Kim3, et al. Relationship between Vitamin D, Parathyroid Hormone, and Bone Mineral Density in Elderly Koreans. J Korean Med Sci 2012; 27: 636-643 Jurutka PW, Whitfield GK, Hsieh JC, Thompson PD, Haussler CA, Haussler MR: Molecular nature of the vitamin D receptor and its role in regulation of gene expression. Rev Endocr Metab Disord 2: 203–216, 2001 CrossRefPubMedGoogle Scholar Maeda S. S., Borba V. Z. C., Camargo M. B. R., et al. Recommendations of the Brazilian Society of Endocrinology and Metabology (SBEM) for the diagnosis and treatment of hypovitaminosis D. Arquivos Brasileiros de Endocrinologia e Metabologia. 2014;58(5):411–433. doi: 10.1590/0004-2730000003388. [PubMed] [CrossRef] [Google Scholar Ning Z., Song S., Miao L. et al., “High prevalence of vitamin D deficiency in urban health checkup population,” Clinical Nutrition, vol. 35, no. 4, pp. 859–863, 2016. View at Publisher • View at Google Scholar • View at Scopus Peacock M. Calcium metabolism in health and disease.Clin J Am Soc Nephrol. 2010 Jan;5 Suppl 1:S23-30. doi: 10.2215/CJN.05910809. Potts JT, Gardella TJ: Progress, paradox, and potential: Parathyroid hormone research over five decades. Ann N Y Acad Sci 1117: 196–208, 2007 CrossRefPubMedGoogle Scholar Holick M. F. and Chen T. C., “Vitamin D deficiency: a worldwide problem with health consequences,” American Journal of Clinical Nutrition, vol. 87, no. 4, pp. 1080S–1086S, 2008. View at Google Scholar • View at Scopus Veldurthy V., Wei R., Oz L., Dhawan P., Jeon Y. H., and Christakos S., “Vitamin D, calcium homeostasis and aging,” Bone Research, vol. 4, Article ID 16041, 2016. View at Publisher • View at Google Scholar Yanoff L. B., Parikh S. J., Spitalnik A., et al. The prevalence of hypovitaminosis D and secondary hyperparathyroidism in obese Black Americans. Clinical Endocrinology. 2006;64(5):523–529. doi: 10.1111/j.1365-2265.2006.02502.x. [PMC free article] [PubMed] [CrossRef] [Google Scholar]
Year 2019,
Volume: 6 , 106 - 110, 25.07.2019
Abstract
Vitamin
D is a fat soluble organic compound, acting like a hormone and playing a
crucial role in calcium homeostasis in the human body. Both vitamin D and
parathyroid hormone are essential in calcium metabolism. This paper aims the
assessment of the current situation of vitamin D status and parathyroid hormone
in Albanians, during the period of time from 2009 to 2014. All the individuals
involved in this study were taken under examination through blood sampling (10
ml/person) to check for the present value of vitamin D and PTH as well as other
parameters, such as calcium, phosphate, etc. PTH and vitamin D levels were
measured by electrochemiluminescence immunoassay, while total calcium and
phosphate values were measured by Turbidimetry method on Coobas 6000 system.
The values of 25(OH) D and PTH were correlated with age, gender and
electrolytes. From the results, we notice a high prevalence of vitamin D
insufficiency in the group with primary hyperparathyroidism (18.15±8.75 ng/ml),
low levels of vitamin D in the group with secondary hyperparathyroidism
(15.71±4.45 ng/ml) and in the group with hypoparathyroidism (15.83±9.31 ng/ml).
We noticed also a negative correlation between 25(OH) D and PTH levels. In
conclusion, we can say that, from this study, it is noticed a high prevalence
of vitamin D deficiency in Albanians, and we can recommend regular blood tests
at a certain age, in order to prevent other diseases linked to low levels or
insufficiency of vitamin D.
References
- Arnold J. Felsenfeld, Mariano Rodriguez, Escolastico Aguilera-Tejero. “Dynamics of Parathyroid Hormone Secretion in Healthand Secondary Hyperparathyroidism” In –Depth Review; Clin J Am Soc Nephrol 2: 1283-1305, 2007. Bellavia D., Costa V., De Luca A., et al. Vitamin D level between calcium-phosphorus homeostasis and immune system: new perspective in osteoporosis. Current Osteoporosis Reports. 2016:1–12. doi: 10.1007/s11914-016-0331-2. [PubMed] [CrossRef] [Google Scholar] Brown EM: The calcium-sensing receptor: physiology, pathophysiology and CaR-based therapeutics. Subcell Biochem 45: 139–167, 2007 CrossRefPubMedGoogle Scholar Cashman K. D., Dowling K. G., Škrabáková Z. et al., “Vitamin D deficiency in Europe: pandemic?” American Journal of Clinical Nutrition, vol. 103, no. 4, pp. 1033–1044, 2016. View at Publisher • View at Google Scholar • View at Scopus Dawson-Huges B, Haeney RP, Holick MF, Lips P, Meunier PJ, Vieth R: Estimates of optional vitamin D status. Osteoporosis Int 16: 713-716, 2005. Guilsun Kim1*, Ki Won Oh2*, Eun-Hee Jang3, Mee-Kyoung Kim3, et al. Relationship between Vitamin D, Parathyroid Hormone, and Bone Mineral Density in Elderly Koreans. J Korean Med Sci 2012; 27: 636-643 Jurutka PW, Whitfield GK, Hsieh JC, Thompson PD, Haussler CA, Haussler MR: Molecular nature of the vitamin D receptor and its role in regulation of gene expression. Rev Endocr Metab Disord 2: 203–216, 2001 CrossRefPubMedGoogle Scholar Maeda S. S., Borba V. Z. C., Camargo M. B. R., et al. Recommendations of the Brazilian Society of Endocrinology and Metabology (SBEM) for the diagnosis and treatment of hypovitaminosis D. Arquivos Brasileiros de Endocrinologia e Metabologia. 2014;58(5):411–433. doi: 10.1590/0004-2730000003388. [PubMed] [CrossRef] [Google Scholar Ning Z., Song S., Miao L. et al., “High prevalence of vitamin D deficiency in urban health checkup population,” Clinical Nutrition, vol. 35, no. 4, pp. 859–863, 2016. View at Publisher • View at Google Scholar • View at Scopus Peacock M. Calcium metabolism in health and disease.Clin J Am Soc Nephrol. 2010 Jan;5 Suppl 1:S23-30. doi: 10.2215/CJN.05910809. Potts JT, Gardella TJ: Progress, paradox, and potential: Parathyroid hormone research over five decades. Ann N Y Acad Sci 1117: 196–208, 2007 CrossRefPubMedGoogle Scholar Holick M. F. and Chen T. C., “Vitamin D deficiency: a worldwide problem with health consequences,” American Journal of Clinical Nutrition, vol. 87, no. 4, pp. 1080S–1086S, 2008. View at Google Scholar • View at Scopus Veldurthy V., Wei R., Oz L., Dhawan P., Jeon Y. H., and Christakos S., “Vitamin D, calcium homeostasis and aging,” Bone Research, vol. 4, Article ID 16041, 2016. View at Publisher • View at Google Scholar Yanoff L. B., Parikh S. J., Spitalnik A., et al. The prevalence of hypovitaminosis D and secondary hyperparathyroidism in obese Black Americans. Clinical Endocrinology. 2006;64(5):523–529. doi: 10.1111/j.1365-2265.2006.02502.x. [PMC free article] [PubMed] [CrossRef] [Google Scholar]
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Details
| Primary Language | English |
|---|---|
| Subjects | Engineering |
| Journal Section | Articles |
| Authors | |
| Publication Date | July 25, 2019 |
| Published in Issue | Year 2019Volume: 6 |
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