Research Article
Year 2019,
Volume: 7 , 308 - 314, 24.11.2019
Abstract
References
- Al-Abachi S ZM (2006) Enzymatic and other biochemical changes in blood serum and tissues of benign and malignant brian cancer. Ph.D. Thesis,College of Science. Mosul University. AL-Gammas ,M.H.A.(2006) Study of physiological and biochemical variables of blood and articular fluid for some patients with pulmonary arthritis. . M.Sc. Thesis .College of Sciences, University of Mosul. Iraq. Al Gubory KH; Bolifraud P; Cermain GN; Cole A; Ceballos Bico TI (2004) Antoxidant enzymatic defence systems in sheep Corpus luteum throughout pregnancy. Soci. Repr.Fert.,128:767-774. AL- Nuaimy .Y.S.A.(2010) Comparison of latex and polymerase sequencing methods in the diagnosis of Toxoplasma gondii in Nineveh province. M.Sc. Thesis .College of education, University of Mosul. Iraq. AL-Robaiey ,.R . F.G.M. (2006) Isolation and Studing Arylesterase in Blood Serum and Its Relation with Atherosclerosis in Mosul. M .Sc. Thesis in chemistry. College of Sciences, University of Mosul. AL-Sabaawy , OM . (2009) Measurement of lipid peroxidation irdices and some antioxidations in both blood and sweat fluid of hypertensive patients. M.Sc. Thesis in Biochemistry ,College of Sciences, University of Mosul. AL Khaffaf, F.H.O.(2001) Isolation and study of epidemiological seroprevalence of toxoplasmosis age in Nineveh province . M.Sc. Thesis .College of Sciences, University of Mosul. Iraq. Ambrosio G and Tritto I (1999) Reperfusion injury experimental evidence and clinical implications. Am.Heart.138:569-575. Beyer W;Mlay J and Fridovich I (1991) Superoxide dismutase. Prog nuclic acid Res.Mol.Biol.,40:221-253. Bartosikova L; Necas J; Suchy V; Kubinova D; Vesela L and Benes L (2003) Effect of morine in alloxan- induced diabetes mellitus in the laboratory rat. Acta Vet.,72:191-200. Buxton D (1983) Toxoplasmosis. In martin WB (ed.) Diseases of sheep. Black well scientific Publication, Oxford. Dawood M N (2007) Study of liver function tests in non pregnant women with toxoplasmosis. M.Sc. Thesis ,College of Medicine University of Mosul. Dubey JP and Livington JR (1986) Sarrcocystis capracanis and Toxoplasma gondii infection in range goat from Texas. Am. J.Vet.,47(3):523-524. Dubey JP (2003) Toxoplasma gondii. Vet. Parasitol., 86:235-248. Gleeson M; Bishop NC; Blannin AK;Burns VE;Lancaster GI; Robson –Ansley P;Walsh NP and Whitham M(2006) Immune function in sport and exercise. Elsevier Churcill Livingston. China., 22,296. Habig W H;Pabst MJ and Jakoby W B (1974) Glutathione S- transferase. the frist enzymatic step in merca pturic acid formation. J. Biochem., 249(22):7130-7139. Kabaroglu C; Mutaf I; Boydak B; Ozmen D; Habif S; Erdener D; Polritader Z and Bayindir O (2004) Associatation between serum paraoxonase activity and oxidation stress in acute coronary syndromes . Acta Cordiol.,59(6):606-611. Kaynar H; Meral H; Turhan H; Keles M; Celik G and Acay F (2005) Glutathione peroxidase, glutathione-S- Tansferase, catalase, xanthine oxidase Cu- Zn superoxide , dismutase activities, total glutathione, nitric oxide, and malondialdehyde levels in erythrocytes of patients with small cell and non cancer. Liu J (2003) Classic Glutathione Peroxidase. Free Radical and Radiation Biology Program. The University of Iowa City, IA.52224-228. Michael L (2001) The Peroxy Radical. Department of Chemistry, University of Iowa, Iiwa City, IA.52242. Mohammad FK and Omer St.V.E.V (1982) Modifications of michel’s electrometric method for rapid measurement of blood cholinesterase activity in animals:a minireview. Vel.Hum. Toxicol.,24:119-121. Morris MC ;Evans DA; Bienuas JL;Tangney CC and Wilson RS (2002) Vitamin E and congnitive decline in older persons. J. Arch. Neural.,59:1125-1132. Mla-ALw .F. Y.H (2011) Oxidative stress for pregnancy in the Ninawa governorate. M .Sc. Thesis in Biochemistry. College of Sciences, University of Mosul. Nevin D; Zambon A; Furlong CE; Richter R J; Humbert R; Hokonson JE and Brunzell JD (1996) Paraoxonase genotyper, lipoprotein lipase activity and HDL. Arteriosclar. Thromb. Vasc.Biol.,16:1243-1249. Prescott LM; Harley JP; Klein DA (2002) Microbiology (5th ed.). McGraw Hill. New York. Remington JS; McLeod R; Thulliez P; Desmants G (2000) Toxoplasmosis: In Remington JS; Klein JO Infectius diseases of the fetus and new born infants". (5th ed.) .WB Saunders Rodrigo R; Prat H and Passalacqua W (2007) Relationship between oxidative stress and essential hypertension .J.Cardiovasc Pharmacol.,46:1159-1167. Robinson IP; Yamka RM and Friesen K G (2008) Food with lipoic acid and elevated levels of vitamin E and vitamin C correlate with whole blood antioxidant concentrations and may protect geriatric dogs form oxidative stress. Int. J. Appl. Res. Vet. Med., 6(2):93-100. Rodrigo R; Prat H and Passalacqua W (2007) Relationship between oxidative stress and essential hypertension .J.Cardiovasc Pharmacol.,46:1159-1167. Senti M; Tomas M; Fito M; Weinbernner T; Covas M; Sala J; Masia R and Marrugat J (2003) Antioxidant paraoxonase 1 activity in the metabolic syndrome J. Clin. Endocrinol.Metab.,88(11):5422-5426. Sharma SP and Dubey JP (1981) Quantitative survival Toxoplasma gondii tachyzoites and bradyzoites in pepsin and trypsin solution. Ann. J. Vet. Res., 42:128-130. Stahl W and Seis H (1997) Antioxidant defense vitamin E and C and carotonoids. Diabetes,46:14-18. Stary PB (1999) Treatment of toxoplasmosis in pregnant mother and new born . Child. Scand. J. Infect. Dis.,84:23-31. Tietz NW (1999) Textbook of Clinical Chemistry. (3rd edn.) W.B.Saunders Company, Philadephia,1239-1250. Tomas M; Senti M; Gareia- Faria F; Vila J; Torrents A;Govas A and Marrugat J (2000) Effect of simvastatin therapy on paraoxonase activity and related lipoprotein in familial hypercholestrolemic patients. Arteriosclar. Thromb. Vasc.Biol.,20:2113. Trinder P (1966) Determination of glucose in blood using glucose oxidase with an alternative oxygen accepted. Am. Clin. Biochem.,6:24. Vasdev S; Gill VD and Singal PK (2006) Madulation of oxidative stress- induced hypertension and atherosclerosis. Exp. Clin.Cardiol.,11(3):206-216.
Effect of Some Biochemical Parameters on the Level of Enzymes in the Serum and Placenta of the Infected Pregnant Woman with Toxoplasmosis
Abstract
The present study was conducted aiming at investigating the medical, biological and biochemical importance of toxoplasmosis and the effect of the causative agent, Toxoplasma gondii ,on the level of the enzymes in the serum and placentae of infected pregnant women compared to non- pregnant, non- infected women (control group) he study included 450 specimens of women , 225 out of them were non- infected and 225 were infected with toxoplasmosis.A significant increase (p≤0.01) in activity of Px, GST ,LDH and AchE whereas non-significant decrease in activity of SOD and AE was noticed, compared to control group.Interference between infection and different pregnancy periods showed a significant increase (p≤0.01) in activity of SOD, Px, LDH and AE in serum of pregnant, infected women during 1-3 months pregnancy period , whereas GST increased significantly (p≤0.01) in activity during 3-6 months pregnancy period and AchE during 6-9 months pregnancy period.The result related to the placentae of the pregnancy women who are infected with Toxoplasmosis showed a non-significant increasing in activity of: SOD, GST, LDH, and AchE through period of pregnancy ranged (6-9) months. Also; efficiency of AE increased through period of pregnancy ranged (1-3) months; but activity of Px through period of pregnancy in placentae of the pregnant infected women decreased.
References
- Al-Abachi S ZM (2006) Enzymatic and other biochemical changes in blood serum and tissues of benign and malignant brian cancer. Ph.D. Thesis,College of Science. Mosul University. AL-Gammas ,M.H.A.(2006) Study of physiological and biochemical variables of blood and articular fluid for some patients with pulmonary arthritis. . M.Sc. Thesis .College of Sciences, University of Mosul. Iraq. Al Gubory KH; Bolifraud P; Cermain GN; Cole A; Ceballos Bico TI (2004) Antoxidant enzymatic defence systems in sheep Corpus luteum throughout pregnancy. Soci. Repr.Fert.,128:767-774. AL- Nuaimy .Y.S.A.(2010) Comparison of latex and polymerase sequencing methods in the diagnosis of Toxoplasma gondii in Nineveh province. M.Sc. Thesis .College of education, University of Mosul. Iraq. AL-Robaiey ,.R . F.G.M. (2006) Isolation and Studing Arylesterase in Blood Serum and Its Relation with Atherosclerosis in Mosul. M .Sc. Thesis in chemistry. College of Sciences, University of Mosul. AL-Sabaawy , OM . (2009) Measurement of lipid peroxidation irdices and some antioxidations in both blood and sweat fluid of hypertensive patients. M.Sc. Thesis in Biochemistry ,College of Sciences, University of Mosul. AL Khaffaf, F.H.O.(2001) Isolation and study of epidemiological seroprevalence of toxoplasmosis age in Nineveh province . M.Sc. Thesis .College of Sciences, University of Mosul. Iraq. Ambrosio G and Tritto I (1999) Reperfusion injury experimental evidence and clinical implications. Am.Heart.138:569-575. Beyer W;Mlay J and Fridovich I (1991) Superoxide dismutase. Prog nuclic acid Res.Mol.Biol.,40:221-253. Bartosikova L; Necas J; Suchy V; Kubinova D; Vesela L and Benes L (2003) Effect of morine in alloxan- induced diabetes mellitus in the laboratory rat. Acta Vet.,72:191-200. Buxton D (1983) Toxoplasmosis. In martin WB (ed.) Diseases of sheep. Black well scientific Publication, Oxford. Dawood M N (2007) Study of liver function tests in non pregnant women with toxoplasmosis. M.Sc. Thesis ,College of Medicine University of Mosul. Dubey JP and Livington JR (1986) Sarrcocystis capracanis and Toxoplasma gondii infection in range goat from Texas. Am. J.Vet.,47(3):523-524. Dubey JP (2003) Toxoplasma gondii. Vet. Parasitol., 86:235-248. Gleeson M; Bishop NC; Blannin AK;Burns VE;Lancaster GI; Robson –Ansley P;Walsh NP and Whitham M(2006) Immune function in sport and exercise. Elsevier Churcill Livingston. China., 22,296. Habig W H;Pabst MJ and Jakoby W B (1974) Glutathione S- transferase. the frist enzymatic step in merca pturic acid formation. J. Biochem., 249(22):7130-7139. Kabaroglu C; Mutaf I; Boydak B; Ozmen D; Habif S; Erdener D; Polritader Z and Bayindir O (2004) Associatation between serum paraoxonase activity and oxidation stress in acute coronary syndromes . Acta Cordiol.,59(6):606-611. Kaynar H; Meral H; Turhan H; Keles M; Celik G and Acay F (2005) Glutathione peroxidase, glutathione-S- Tansferase, catalase, xanthine oxidase Cu- Zn superoxide , dismutase activities, total glutathione, nitric oxide, and malondialdehyde levels in erythrocytes of patients with small cell and non cancer. Liu J (2003) Classic Glutathione Peroxidase. Free Radical and Radiation Biology Program. The University of Iowa City, IA.52224-228. Michael L (2001) The Peroxy Radical. Department of Chemistry, University of Iowa, Iiwa City, IA.52242. Mohammad FK and Omer St.V.E.V (1982) Modifications of michel’s electrometric method for rapid measurement of blood cholinesterase activity in animals:a minireview. Vel.Hum. Toxicol.,24:119-121. Morris MC ;Evans DA; Bienuas JL;Tangney CC and Wilson RS (2002) Vitamin E and congnitive decline in older persons. J. Arch. Neural.,59:1125-1132. Mla-ALw .F. Y.H (2011) Oxidative stress for pregnancy in the Ninawa governorate. M .Sc. Thesis in Biochemistry. College of Sciences, University of Mosul. Nevin D; Zambon A; Furlong CE; Richter R J; Humbert R; Hokonson JE and Brunzell JD (1996) Paraoxonase genotyper, lipoprotein lipase activity and HDL. Arteriosclar. Thromb. Vasc.Biol.,16:1243-1249. Prescott LM; Harley JP; Klein DA (2002) Microbiology (5th ed.). McGraw Hill. New York. Remington JS; McLeod R; Thulliez P; Desmants G (2000) Toxoplasmosis: In Remington JS; Klein JO Infectius diseases of the fetus and new born infants". (5th ed.) .WB Saunders Rodrigo R; Prat H and Passalacqua W (2007) Relationship between oxidative stress and essential hypertension .J.Cardiovasc Pharmacol.,46:1159-1167. Robinson IP; Yamka RM and Friesen K G (2008) Food with lipoic acid and elevated levels of vitamin E and vitamin C correlate with whole blood antioxidant concentrations and may protect geriatric dogs form oxidative stress. Int. J. Appl. Res. Vet. Med., 6(2):93-100. Rodrigo R; Prat H and Passalacqua W (2007) Relationship between oxidative stress and essential hypertension .J.Cardiovasc Pharmacol.,46:1159-1167. Senti M; Tomas M; Fito M; Weinbernner T; Covas M; Sala J; Masia R and Marrugat J (2003) Antioxidant paraoxonase 1 activity in the metabolic syndrome J. Clin. Endocrinol.Metab.,88(11):5422-5426. Sharma SP and Dubey JP (1981) Quantitative survival Toxoplasma gondii tachyzoites and bradyzoites in pepsin and trypsin solution. Ann. J. Vet. Res., 42:128-130. Stahl W and Seis H (1997) Antioxidant defense vitamin E and C and carotonoids. Diabetes,46:14-18. Stary PB (1999) Treatment of toxoplasmosis in pregnant mother and new born . Child. Scand. J. Infect. Dis.,84:23-31. Tietz NW (1999) Textbook of Clinical Chemistry. (3rd edn.) W.B.Saunders Company, Philadephia,1239-1250. Tomas M; Senti M; Gareia- Faria F; Vila J; Torrents A;Govas A and Marrugat J (2000) Effect of simvastatin therapy on paraoxonase activity and related lipoprotein in familial hypercholestrolemic patients. Arteriosclar. Thromb. Vasc.Biol.,20:2113. Trinder P (1966) Determination of glucose in blood using glucose oxidase with an alternative oxygen accepted. Am. Clin. Biochem.,6:24. Vasdev S; Gill VD and Singal PK (2006) Madulation of oxidative stress- induced hypertension and atherosclerosis. Exp. Clin.Cardiol.,11(3):206-216.
There are 1 citations in total.
Details
| Primary Language | English |
|---|---|
| Subjects | Engineering |
| Journal Section | Articles |
| Authors | |
| Publication Date | November 24, 2019 |
| Published in Issue | Year 2019Volume: 7 |
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.