Abstract
The study of blood microcirculation has revealed specific properties that distinguish blood from
Newtonian and non-Newtonian fluids. These anomalies cannot be fully explained by conventional
hydrodynamic or rheological models alone. While the viscous incompressible fluid model describes blood flow
well in vessels with diameters exceeding 300 µm, capillaries below this threshold exhibit non-classical flow
behavior, the underlying physical mechanisms of which remain an active area of investigation. In this work,
blood is modeled as a multiphase physicochemical system, represented as a suspension of cellular elements in
plasma. The cellular components, particularly erythrocytes, are treated as part of an electrostatic system, where
their electrical characteristics are determined not by discrete surface charges, but by the zeta potential -the
electrokinetic potential at the interface between the erythrocyte membrane and the plasma. Microcirculatory
dynamics are analyzed through the framework of DLVO theory. A quantitative assessment of red blood cell
motion in capillaries is presented, incorporating resistance forces, hydrodynamic pressure, and gradients in
electrostatic potential. The results indicate that mechanical and electrical factors substantially influence
microcirculatory flow, affecting erythrocyte deformation and orientation, and inducing a directional electrostatic
force gradient that governs cell movement in narrow capillaries.
References
- Kalandadze, L., Gomidze, N. & Kontselidze, M. (2025). Investigation of red blood cell microcirculation using the DLVO theory. The Eurasia Proceedings of Science, Technology, Engineering and Mathematics (EPSTEM), 36, 73-80.
Details
| Primary Language | English |
|---|---|
| Subjects | Classical Physics (Other) |
| Journal Section | Articles |
| Authors | |
| Early Pub Date | October 31, 2025 |
| Publication Date | October 31, 2025 |
| Submission Date | July 1, 2025 |
| Acceptance Date | August 5, 2025 |
| Published in Issue | Year 2025 Volume: 36 |
