The Relationship between Zinc, Copper and Manganese Levels on Bone Formation, Which Increases the Risk of Uterine Cancer

Abstract

Due tothe lack of previous studies on the impact of osteoporosis on the incidence ofuterine cancer, and the rapid spread of uterine cancer in recent years all theworld, and the exact mechanism of its occurrence is not entirely clear. Thestudy focused on the possibility of consideration of osteoporosis as a markerto uterine cancer by study the relationship between osteoporosis and uterine cancerthrough the measurement of both Zinc, Copper and Manganese which operate insidethe body as antioxidation when its linked with enzymes, which affect the bonedensity and their impact on the incidence of uterine cancer. The study involvedcollecting samples from hospitals in Mosul, women without uterine cancer as thecontrol group and divided into two groups (44 women with good health and 38women diagnosed as osteoporosis only). And patients women also divided to thetwo groups did not receive any treatment (43 with uterine cancer only and 58women with osteoporosis and uterine cancer). Each patient was evaluatedclinically and then was estimated Zinc, Copper and Manganese in serum usingatomic absorption spectroscopy technique as well as appreciation of bothestrogen and progesterone in the serum. The results showed that osteoporosismay increase the incidence of uterine cancer through hormonal changes and theconcentration of antioxidants and their impact on the bone-building and thusits impact on the amount of free radicals in the body which cause increase thelikelihood of uterine cancer before and after menopause. The study showed thatosteoporosis is a new risk factors increase the likelihood of uterine cancer.Women should pay attention to bone health by maintaining the concentration ofantioxidant mineral, which has a role in bone health and prevent fragility andearly diagnosis and treatment of osteoporosis to reduce the risk of uterinecancer.